Ubinuclein 1 (UBN1) is a ubiquitously expressed evolutionarily conserved protein which binds to proliferation-promoting genes that are repressed by formation of senescence-associated heterochromatin foci (SAHF). Ubinuclein 1 associates with various transcription factors and with histone methyltransferase activity, is indispensable for SAHF formation and appears to be a regulator of senescence. Although in most cells ubinuclein is localized to the nucleus, in cells forming tight junctions it is recruited to the cell adhesion complexes, dependently on the cell density.
HIRA-binding protein; Protein VT4; Ubinuclein-1; Ubiquitously expressed nuclear protein; VT VT4 HIRA-binding protein ubinuclein-1 ubiquitously expressed nuclear protein
Cat # 15772152
100 µL
Cat # 17136308
100 µg
Cat # 17149433
100 µL
Cat # 16086966
100 ug
Cat # 12362453
100 µg
Cat # 16619814
100 µL
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